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The Sperm Cell - Production, Maturation, Fertilization, Regeneration (2nd Ed)
' F) h: f* O0 S" Z. E5 j0 a1 f; zby Christopher J. De Jonge, Christopher L. R. Barratt
" G! T$ l5 y9 NCambridge University Press | July 2017 | ISBN-10: 1107126320 | 316 Pages | PDF | 22.7 mb
. A- @% L6 S" S x% @9 |: A6 w* shttps://www.amazon.com/Sperm-Cell-Production-Fertilization-Regeneration/dp/1107126320
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6 u: Q2 y5 D( P2 G8 `3 T4 V: w9 RThis revised and updated second edition provides a comprehensive account of the human male gamete. Detailed overviews of human sperm production, maturation, and function - and how these processes affect and influence fertility, infertility, and assisted reproduction - are given. A wide range of new developments including proteomics, spermatogenesis, sperm-specific WW domain-binding proteins, Ca2+ signalling, DNA packaging, epididymis are explored, whilst a new chapter presents information gained from mouse genetics, highlighting how it informs male fertility research. The impact of environmental factors during pre-pubertal and pubertal stages of life is also investigated. Featuring engaging prose with chapters organized topographically, The Sperm Cell remains an essential resource for andrologists, clinical scientists, and laboratory personnel.# J, {8 t) C( [& M
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About the Authors# i1 J; F5 r) g) j& U1 Q/ u8 ~ x
Christopher De Jonge is Director of the Andrology Program at the University of Minnesota Medical Center and Adjunct Professor in the Department of Urology at the University of Minnesota.8 ~7 Q) G& r' J% Y T3 d
Christopher L. R. Barratt is Professor of Reproductive Medicine at the School of Medicine, University of Dundee, Ninewells Hospital, Dundee.& _6 M. Y/ V6 l
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CONTENTS% k/ e# T# n! a0 n: `' \; P
List of Contributors page vii9 c; j/ ?, K& P
Foreword by Ryuzo Yanagimachi x4 W1 W3 g# `1 W
Preface xiii0 `" w/ G2 t e4 y% X+ F8 `# a
1 Spermatogenesis: Clinical and Experimental Considerations 1
+ r# G$ I" g' b) Q% ?9 ^5 s2 Sperm Chromatin Stability and Susceptibility to Damage in Relation to Its Structure 21
4 Q0 A( `+ X/ k- W. Y3 Sperm Ultrastructure in Fertile Men and Male Sterility: Revisiting Teratozoospermia 366 `2 S2 i# @; L# t. e* D) g5 V) r
4 Sperm RNA and Its Use as a Clinical Marker 59# l n" b4 f1 F* u4 j" w
5 Role of the Epididymis in Sperm Maturation 733 X% Y" E' R4 V0 ~6 b
6 Seminal Plasma Plays Important Roles in Fertility 88
& G) ]0 x- r j# m* Z& A1 S8 e7 Physiological and Pathological Aspects of SpermMetabolism 109
( K: m7 z# X$ Y# g# Q# f% P8 Regulation of Sperm Behaviour: The Role(s) of [Ca2+]i Signalling 126
$ N7 ]& `' Y' R4 c/ q1 w9 Proteomics of Capacitation 143
/ l0 O! N }. @# K; m* `10 Current Concepts and Unresolved Questions in Human Sperm Cumulus and Zona Interaction 152
1 e2 m5 ^3 L( |, T7 ?1 i5 @! f11 Sperm-SpeciicWW-Domain-Binding Proteins 157
2 l: m, i0 `& x: B3 z12 Fundamental Role for Sperm Phospholipase C in Mammalian Fertilization 177
l; @# j5 r! K13 Male Infertility and Assisted Reproduction 193
- ?. l* J3 T0 ]% Y! E( N9 u4 s14 The Genetic Basis ofMale Infertility 208
2 s+ H+ F0 E( Q u15 The Sperm Epigenome 230
1 A" \: K, L! ~4 z; u( q2 z; x16 Environmental Factors andMale Fertility 240+ G2 A- }; F8 G9 I" L
17 Susceptibility of the Testis to Lifestyle and Environmental Factors During the Life Course 260: V+ t% v+ J8 _+ x( r9 M. {
18 Mouse Genetics – How Does It Inform Male Fertility Research? 280
2 D" {5 S5 H7 Z. B6 L8 s" ~* C* LIndex 297
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发表于 2017-6-3 18:52:06
